Thursday, September 23, 2010

Serial killer!



Well, I thought I shouldn't write this on a public forum. But this is one significant day of my life, so much so that I just can't let it skip by without a trace. (No charges against me/my lab or anyone related to me for this, no factual things quoted in this post. All procedures approved by animal welfare committees concerned).

This was a day that marks the acceptance of me as a researcher by myself. Today was the day I did a surgery on a mouse and made slices out of its brain. I did that all by myself for the first time today, though I had watched it being done a couple of more times before. Well to watch it and to do it are totally different things altogether, as I now realize.

Morning I dropped in just to watch Anne-Marie perform the surgery( I am for sure going to remember her for long for teaching me so patiently, others in the lab deserve a mention too). Once she was done, she suggested I do it from scratch all by myself. And I really wanted to get over my inhibitions for doing it, so I did it eventually. I was pretty confident about the steps to be followed in the animal house, or so did I think, then. Infact during the first surgery of the day that I watched, I picked up the mouse from the animal house. So I thought it wasn't really a big deal. So I go in to that isolated animal house, all by myself, nobody even anywhere close except stinking mice. Do all the protocols that I am supposed to, fully armed, totally clean into the cage room. I take out the cage and there, four cute nice fluffy shiny mice, playing with each other as if today was the last day of their life. Yes, it was going to be. All they knew was the food that was in there. And a huge pair of hands over them trying to wave to them!

Then came the most horrible part - all I had to do was to catch it by its tail and then put it onto another box so that I can take it to my bench. There I froze. Just froze, couldn't think, couldn't move. My heart pumping in my mouth, for that little thing. Not that I am a big fan of animals in general, nor am I one of those who create a big hue and cry about use of animals in research. But to DO it, omg, I would have had a cardiac arrest!

So I waited and waited and waited... Put the cage back, took it out once again,.. Waited.. Waited... all the while, talking to myself, cheering myself up, apologizing to the mice, talking to them, telling small prayers to them! OMG, you might think I am crazy, but I am what I am, the least I can do to that little thing out of which I make my bread and butter.

Once I did that, the rest was OK, not as horrifying as it was earlier. Even the decapitation part of it looked simple enough. But it has made this day an eventful one. Makes me wanna think, "that's life ain't it? TRANSIENT". What's a good day's work to one person, costs the life to another. Unfortunately the analogy doesn't stop with the equation between a researcher and a mouse alone, it applies to much higher examples. And it isn't even survival of the fittest in this - you would be the first one to be 'sacrificed' if you were the best of the lot! Makes my faith in destiny grow stronger!!

All said, when I had the brain slices in my hand, my joy knew no bounds, I wanted to go tell the entire world that I had done that! It was everyday work for people here, nothing even close to a special moment, but only a corner of my heart knows that it was a bet against myself, against my inhibitions and what I thought was the limit of my ability. Now, I don't know if i even did it correctly, if it was what ideally a good slice should be. But I crossed the lag phase. I am happy to have made a beginning.

God help me with the rest, as always.

How much work can get me thinking!

Sunday, September 19, 2010

Ambition and Content - Mutually Exclusive?

OK, so I am one month into what I thought I would never be - a PhD student! A phase of life in which it is very easy to get so engrossed in work, when little things don't matter, when raindrops are no more special, when food is just to satisfy your hunger pangs, when what you do on a phone call diminishes to the matter-of-factly voicemail (indeed, there's a sea of difference between what you talk on both and how you talk) when you forget to see a person behind a professional, when your world becomes too small and work too precious, even more precious than a small happy contented life. So here's the big question? Is chasing an ambition worth sacrificing all the content that life would have offered you otherwise? Do you even have a choice? Is the ambition worth all the travails and efforts of chasing it?

This is when I read this article by on the O-zone column by Vinita, a TOI columnist, someone's words really strike a chord with me. I am putting it up here, no copyright violation issues please. (I am at CMU, remember? :P) So here it is, with all due credit to her.

Ambition and a contented personal life need not be contradictory to each other. Don’t make your ambition impossible to achieve!


Are less ambitious people better off than those who are wildly competitive? Is life a better deal for those who are average students, get a decent degree, find themselves a secure job and settle down comfortably in it? Now all they need to worry about is securing a happy home life, bringing up normal, average kids and living happily ever after! Probably here too the standards they set themselves are not too high and so, with lower expectations, their chances of disappointment are much lower too.

Rahul Sharma (name changed), a colleague, talks of a friend who years ago told him he didn’t want to ever grow beyond a GM. “I found it very strange then,” says the highly competitive self-flagellating colleague, “but now as I find myself with no time for myself and just a weekend relationship with my wife as bosses and work take over all my waking hours, I think my friend was pretty smart! Today, he has chosen a career and lifestyle that may not be cutting- edge, but which gives him enough time for the rest of his life!”

I cannot believe that Rahul seriously meant it, because if he did, what’s to stop him from throwing in the towel even now? The fact that he will not do so means that he holds his drive, his ambition and his goals dear, and is willing to make the required sacrifices for the same. As all those with overriding dreams and ambition do.

However Rahul goes on, “The pace of my life is such that I don’t know how eight months of this year have passed by. I have no time to remain in touch with friends since I work round the clock to keep up with competition. Age is catching up and I know soon I will be old with hardly any intimate friends left. I am familiar with a lot of people courtesy Facebook but on social media sites like FB, we are trading intimacy with familiarity. The digital world is crazy and addictive and perhaps we are attracted to it since we decide when we open and shut conversations with Facebook friends.”

Says another friend, “I am increasingly finding myself feeling lonely in the middle of all the work and projects and even with family around. I think it is the lack of “me” time that makes me feel so. Maybe I’m missing my own company, my own thoughts. Or, maybe I am missing being with close friends. That is when I seek out people on FB. There is no time to be intimate — physically, mentally, spiritually — either with yourself or someone close.”

And yet how would we be any different from animals if all we did was eat, sleep and exist in the small space we call ours and be happy to mark its boundaries as ours? What is life if not an aspiration, a stretch to reach out to the next goal. It is that aspiration, no matter how unattainable the goal, which lifts us above our circumstances and helps better our lives. If a carpenter were to dream of being the country’s Prime Minister, chances are that he may at least end up setting up a small business for himself and carve out a better life for his children. On the other hand, if resigned to his lot, he were to have no ambition, he would die a carpenter and so would his future generations. An impossible dream may shape a better reality for him.

The problem is not with the dreaming, but with making that dream an obsession; not with ambition, but with making that drive the be-all and end-all of your existence. Ambition and a contented personal life need not be contradictory to each other. We should be able to distinguish between ambition that is within the realms of possibility and that which may be an impossibility to achieve. Knowing that, we need to strike a balance between overriding ambition and a contented personal life. There are phases when one needs to give one’s all to work and others when one needs to step back with equal confidence and give due importance to one's personal life. Balance and time management is the key — certainly not as easy as it sounds!

For those of us who are ambitious, there are times in life when it becomes a heavy burden to bear. There are testing times when we are stretched and stressed and all the angst just doesn’t seem worth it. It is at this time that the decision has to be made whether to fight on and may be live like a king some day, or to give up and crawl through the rest of your lives.

As British philosopher John Stuart Mill said, it is possible to be “content with life” even though “dissatisfied”, so long as one has the proper balance of pleasure, quantitatively and qualitatively. In his words, “better Socrates dissatisfied than a pig satisfied.” Who in their right mind would want to lead the life of a pig with no questions of the world, no complaints and no ambition? Socrates with his dissatisfied mind, his curiosity and mental turmoil would certainly be the choice of every rational person.

Bouts of high-adrenaline ambition interspersed with moments of a quiet content would be the ideal recipe for a life well lived!


So here's wishing you, the reader on of those meaningful, content, complete lives, may you find the right balance!

Thursday, September 9, 2010

Funnnnyyyy!!!

http://www.youtube.com/watch?v=mB7fnIlmyzA

Monkeys are adorable, aren't they?! :P